The ending of From Russia with Love resolves in Venice, where Tatiana Romanova shoots Rosa Klebb just as Klebb is about to kill Bond, and the Lektor ends up safely in British hands. Bond then throws away the film footage of himself and Tatiana, and the two ride a gondola through the city.
The finale answers a setup laid in Istanbul. Tatiana and Bond are secretly filmed together, and SPECTRE's plan needs that footage to humiliate him as well as to cover the theft of the machine. When Bond tosses the reel away on the gondola, the revenge plot ends on a personal note, not a political one. The film began with a decoding machine and ends with an object about Bond himself.
Klebb's attack is also the second time the film stages a killer hiding in plain sight. On the Orient Express, Red Grant, played by Robert Shaw, joins the train posing as a British agent, and Bond works out the truth before the brutal compartment fight, which was built on Pinewood Studios train sets. In Venice, Klebb, played by Lotte Lenya, arrives disguised as a hotel maid with a poisoned blade in her shoe. Both threats come from SPECTRE and both rely on disguise, so the last scene echoes the train sequence on a smaller stage: Grant is beaten by Bond in a struggle, while Klebb is beaten by the person she thought she controlled.
It could be argued that the ending works because Tatiana decides it. Her whole role began as a lie told to her by SPECTRE, and the shot that kills Klebb is the moment she stops being a pawn. That gives the Bond girl more agency here than a plot built around a seduction would suggest, though that is a matter of taste and an opinion, not a documented fact.
The film also differs in structure from Dr. No, the entry before it. According to Cord Cutters News, From Russia with Love had a larger budget than Dr. No and introduced the pre-title sequence and Desmond Llewelyn as Q. The result is a film that spends its first hour on slow, spy-versus-spy maneuvering in Istanbul, then turns into a chase across Scotland, Switzerland and Venice, with the helicopter and boat pursuit coming only after the train. My reading, and it is only that, is that the long build makes the quick Venice resolution land harder than a bigger final set piece would.
The closing detail matters for the series. Ernst Stavro Blofeld, SPECTRE's leader (seen with Anthony Dawson on screen and voiced by Eric Pohlmann, both uncredited according to TMDB), is not caught, so the group stays a danger for later films, and the series next moves to Goldfinger.
