In Fast X, Dante Reyes lures Dominic Toretto's crew into a trap in Rome, scatters the family across the world, and ends with Dom driving off a dam in Portugal. Dom's crew takes an Agency job to steal a computer chip in Rome, while Dom, Letty Ortiz and Little B stay home. Cipher arrives wounded and warns that Dante Reyes has turned her people against her. Dante Reyes wants revenge on Dom for his father's death and the loss of the family fortune.
Little Nobody confirms that the Agency never sent a mission to Rome, so Dom, Letty Ortiz and Little Nobody race to save the team. The truck carries a neutron mine that Dante Reyes sets off by remote, and Dom shoves it into the Tiber to limit the blast. Letty Ortiz is arrested, and Aimes, who is in charge of the Agency, blames Dom's team and orders a manhunt.
In Los Angeles, Jakob Toretto saves Mia Toretto and Little B and takes the boy to Portugal. Tess uses the God's Eye surveillance program to find Dom in Naples and points him to Dante Reyes in Rio. There, Dom races Dante Reyes, who kills Diogo with a car bomb after Dom chooses to save Isabel. Tess then shoots Letty Ortiz, who is taken to a secret facility where Cipher is also held, and the two work out that it is in Antarctica.
Dom's team asks Deckard Shaw for help in London, and Shaw agrees but leaves to protect his mother from Dante Reyes's men. Aimes catches Dom in Rio, but Dante Reyes intercepts them on a bridge, a sniper wounds Tess, and Dante Reyes steals God's Eye, so Aimes joins forces with Dom.
Dante Reyes kidnaps Little B in Portugal, and Jakob Toretto sacrifices himself to stop the pursuing mercenaries. Dante Reyes reveals that Aimes is his partner and shoots down a plane carrying Roman Pearce, Tej Parker, Ramsey and Han Lue. Dom drives off a dam with Little B while Dante Reyes sets off explosives planted there, and the film ends on a cliffhanger. In Antarctica, Gisele Yashar, thought dead, emerges from a submarine and rescues Letty Ortiz and Cipher.
